Overview

By leveraging principle of material science and organic chemistry, we develop dynamic hydrogel-based biomaterials, and apply them to understand cell-biomaterial interactions, build disease models and improve ocular regeneration through the delivery of biotherapeutics and stimuli-responsive biomaterials. Our research program stands out through the integration of three key elements, fostering a highly innovative approach: (1) Expertise in engineering hydrogel biomaterials from molecular to micro-scale. (2) Expertise in evaluating cell-biomaterial interactions, and (3) Unique focus on leveraging mechano-transduction and immune-modulation to enhance ocular regeneration.

This research trajectory builds upon Dr Rizwan’s doctoral work in hydrogel biomaterials for corneal tissue engineering (Evelyn Yim Lab) and award-winning postdoctoral work in University of Toronto on the development of photo-tunable hydrogels for 3D cell culture (Molly Shoichet Lab).

COLLABORATORS

Our research is amplified by a network of collaborations with clinicians and scientists. This collaboration empowers us to develop translational biomaterials that offer tangible benefits in addressing ocular blindness, and expanding into new research directions.

Our current collaborators:

Dr. Jod Mehta, Singapore National Eye Center

Dr. Gary Yam, Univ of Pittsburgh Ophthalmology

Dr. Ibrahim Ozbolat, Penn State

Dr. Leonardo Morsut, Univ of Southern California

Dr. Claudia Loebel, Univ of Michigan

Dr. Sangyoon Han, Michigan Tech

FUNDING

Our research is currently funded by:

  • R01 award from National Institute of Health (NIH) National Eye Institute (NEI)

  • R15 award from National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

  • Michigan Tech new lab startup fund